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No, they are completely different

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Notably taking retatrutide for 40 weeks is previously reported (TRANSCEND-T2D-1), to have helped type-2 diabetes patients loose up to 16.8 per cent of their body fat and reduced HbA1c levels by 1.72 per cent

Lilly reported that orforglipron lowered weight by an average of 10.5 per cent (22.9 lbs) compared to 2.2 per cent (5.1 lbs) with a placebo. Later, in even more advanced trials, the pill helped participants lose nearly 12 percent of their body weight over 72 weeks, around 27 pounds for the average person enrolled